"Probably because, contrary to macrophile and kaiju enthusiast portrayal, explosive munitions would be pretty damn effective against a large organic being. "Thick skin" has nothing on the type of materials they were intended to be used against."
I've thought about that, and I've always wanted to see a story that tried to be realistic about that kind of thing and went from there. I was going to try to be relatively realistic in the war scenes in Pax Romana: Not even a 60-foot woman will be able to take a catapult to the face and walk away unscathed. And even tiny spears, arrows, etc could take their toll in large enough numbers. So even giantesses would want to wear armor in a battle...
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